In individual HCC cell lines, Gao et al[113] confirmed that Notch1 activation plays a part in tumor cell growth. healing perspectives. Even though the dedifferentiation of mature hepatocytes/cholangiocytes in hepatocarcinogenesis can’t be excluded, neoplastic transformation of the stem cell subpopulation even more explains hepatocarcinogenesis easily. Elimination of liver organ cancers stem cells in liver organ … Continue reading In individual HCC cell lines, Gao et al[113] confirmed that Notch1 activation plays a part in tumor cell growth